In 2002, First Ladies of Africa came together to form the Organization of African First Ladies against HIV/AIDS (OAFLA), with the objective to be a united voice for Africa’s most susceptible citizens; women and children living with and affected by HIV and AIDS. Along the years, OAFLA has evolved to become an institution that is able to offer a continent-wide leadership in terms of advocacy in the areas of HIV and a broad range of maternal and child health intervention.